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What is Asthma?

The word asthma has originated from an ancient Greek word meaning panting. Essentially asthma is a chronic and recurring inflammation of the air ways (bronchi) that results in obstruction of air flow. Asthma is very common all over the world, in all age groups. It may start in as early as months old baby to elder age group. Asthma is largely controllable and to an extent curable, depending on the stage and extent of the disease.

What happens in Asthma? (Pathogenesis)

There is a decrease in the lumen of the air ways resulting from a two fold response to the allergens and other irritants. Primarily in a hyper reactive response, the smooth muscles in the airways constrict and narrow excessively. Followed by an inflammatory response where the immune system responds to the allergens by sending white blood cells and other immune factors to the airways. These inflammatory factors cause a swelling of the airways and also an increase in the mucus secretion thus causing symptoms like wheezing, cough and shortness of breath.

Prevalence

Children aged 2-12 years reported higher rates of asthma (15.7%) than adults aged 16 years and over (10.1%). In males, the prevalence of asthma was highest among children aged 2-12 years; in females, prevalence was highest among young adults aged 16-24 years. Asthma is also closely linked to allergies. Most, but not all, people with asthma have allergies. Children with a family history of allergy and asthma are more likely to have asthma.

Symptoms of Asthma:

The most common symptoms are

  • Cough
  • Difficulty in breathing
  • Mucus production
  • Exhaustion

The most important and distressing symptom is the breathlessness or sense of suffocation, which may be of varying intensity. Some patients may not have cough or mucus production (expectoration) at all.

The symptoms of asthma may be

  • Periodical (once in a a week to once in a year)
  • Seasonal (a few weeks in a year)
  • Continuous (all throughout or most of the time)

The symptoms might get triggered by one or more of the following:

  • Physical exertion
  • Change in weather or temperature
  • Infection
  • Mental stress
  • Exposure to pollution (dust, chemical, pollen, etc.)
  • Without any apparent reason

Asthma Causes: Factors Responible for Asthma

Asthma has no single cause. It is caused my multiple factors, which can be divided in two groups:

01 External

02 Internal

Asthma is caused and maintained by more than one of the following causes:

  • Genetic or hereditary cause
  • Environmental factors (pollution, pollen, etc) - Systemic diseases
  • Mental stress
  • Allergens

Asthma has a tendency to recur and get chronic. It is often observed to be a life long disease like diabetes or high blood pressure.

One or more of the above factors lead to altered immunity which eventually leads to chronic asthma. It may be noted that the genetic tendency for asthma forms soil, leading to susceptibility to be affected by other external or internal trigger factors.

Allergies Causing Asthma

Allergens Causing Asthma:

  • Pollens
  • Air pollutants
  • Smoking and second hand smoking
  • Respiratory infections
  • Common cold, Sinusitis
  • Exercise, physical exertion
  • Cold air
  • Medications: Aspirin, NSAID, Beta blockers etc.
  • GERD (Gastro esophageal Reflux Disease) Read more on Gerd

The list can be exhaustive though each person may have a different individual or a combination of triggering factors.

Asthma Risk Factors:

The following factors increase your chances of developing Asthma.

  • Urban / Industrial areas where the exposure to environmental pollutants is more.
  • Work Environment - Exposure to chemicals, dust, industrial waste.
  • Heredity - Have a history of either parents or family members suffering from Asthma.
  • Childhood - History of recurrent respiratory tract infections, low birth weight.
  • GERD

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